夏许寒，博士，助理研究员。1995年3月生，2023年毕业于四川大学，获工学博士学位。2023年7月至今，在四川大学食品工程系从事教学科研工作。以第一/通讯作者在TrAc-Trend. Anal. Chem.、 Chem. Eng. J.、 Anal. Chem.、 ACS Sens. (2篇)、 J. Agr. Food Chem. (2篇)、Food Chem.等期刊发表论文12篇，其中中科院一区TOP论文11篇，被引450余次，ESI高被引论文2篇；获授权专利3项；参编英文专著1部，中文专著1部。担任《Biosensors and Bioelectronics》、 《Journal of Hazardous Materials》、 《Journal of Agricultural and Food Chemistry》、 《Food Chemistry》等期刊审稿人。
联系方式：xxh23@scu.edu.cn；xiaxuhanxh@163.com
通讯地址：四川省成都市武侯区四川大学望江校区纺工楼516
研究方向：食源性病原分析，核酸检测与成像，食品安全技术
代表性论文：
(1) Xuhan Xia, Feng Li, Yong Zhang, Yulin Zhu, Sishuo Song, Guiping He, Jiaqi Zhang, Qiang He, Ruijie Deng. Wash-free and high-contrast imaging of single-nucleotide variation in single cells using transcription amplified light-up RNA aptamer. Analytical Chemistry, 2023, 95, 27, 10163-10171
(2)Xuhan Xia, Hao Yang, Jijuan Cao, Jiaqi Zhang, Qiang He, Ruijie Deng. Isothermal nucleic acid amplification for food safety analysis[J]. Trends in Analytical Chemistry, 2022, 153: 116641.
(3)Xuhan Xia, Boheng Ma, Whenhu Zhou, Hao Yang, Yi Dong, Jiaqi Zhang, Qiang He, Ruijie Deng. Direct visualization of single-cell non-repetitive genes by in situ activation of collateral activity of CRISPR/Cas12a inside cells[J]. Chemical Engineering Journal, 2023, 451: 138355.
(4) Xuhan Xia, Boheng Ma, Ting Zhang, Yunhao Lu, Mohammad Rizwan Khan, Yun Hu, Changwei Lei, Sha Deng, Qiang He, Guiping He, Kaixiang Zhang, Ruijie Deng. G‑quadruplex-probing CRISPR-Cas12 assay for label-free analysis of foodborne pathogens and their colonization in vivo. ACS Sensors, 2021, 6: 3295-3302.
(5) Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen, Shijia Wu, Chuxian He, Kaixiang Zhang, Ruijie Deng, Qiang He. Visualization of mycotoxins in living cells using conformation resolved aptamer nanoprobes. ACS Sustainable Chemistry and Engineering, 2020, 8: 9920-9925.
(6)Xia Xuhan, Wang Haibo, Yang Hao, Deng Sha, Deng Ruijie, Dong Yi, He Qiang. Dual-terminal stemmed aptamer beacon for label-free detection of aflatoxin B1 in broad bean paste and peanut oil via aggregation-induced emission. Journal of Agricultural and Food Chemistry, 2018, 66:12431-12438.
（7）Xia Xuhan, Wang Yuxi, Yang Hao, Dong Yi, Zhang Kaixiang, Lu Yunhao, Deng Ruijie, He Qiang. Enzyme-free amplified and ultrafast detection of aflatoxin B1 using dual-terminal proximity aptamer probes. Food Chemistry, 2019, 283:32-38.
(8)Xuhan Xia, Chenxi Zhou, Yulin Zhu, Yi Dong, Qiang He, Mohammad Rizwan Khan, Yuanlong Chi, Rosa Busquets, Ruijie Deng, Yao Ren. Tb3+-nucleic acid probe-based label-free and rapid detection of mercury pollution in food. Food Science and Human Wellness, 2023, https://kns.cnki.net/kcms/detail/10.1750.ts.20221109.1339.002.html.
(9) Ying Wang1, Xuhan Xia1, Minghua Wu, Qiyao Sun, Wei Zhang, Yong Qiu, Ruijie Deng, Aimin Luo, Species-level monitoring of key bacteria in fermentation processes using single-nucleotide resolved nucleic acid assays based on CRISPR/Cas12. Journal of Agriculture and Food Chemistry, 2023, 71, 35, 13147–13155.
(10) Zilan Yuan, Xinmiao Liu, Sha Deng, Guiping He, Jiaqi Zhang, Qiang He, Yuanlong Chi, Xuhan Xia*, Ruijie Deng*. Single-cell genotyping of single-nucleotide mutations using in situ allele-specific loop-mediated isothermal amplification. ACS Sens, 2023 (Accept)
专著：
（1）X Xia, T Zhang, Y Lu, H Yang, Q He, R Deng, In Situ Analytical Tools to Resolve Stress Response Mechanisms of Foodborne Pathogens, 《Stress Responses of Foodborne Pathogens》, 575-607. Springer出版社
（2）第五节：《食源性致病微生物及检测新技术——荧光原位杂交技术》, 中国标准出版社, 2022-05.
国家授权发明专利：
（1）邓锐杰、夏许寒、何强 识别增强型亚稳态核酸适配体探针及在目标物质计数分析中的应用，CN109385426A
（2）邓锐杰、夏许寒、曾红棱、任尧、赵志峰、何强 比例型核酸适配体荧光探针及其检测赭曲霉毒素A的方法，CN109444101A
（3）邓锐杰、夏许寒、何强、杨淏、赵志峰 基于聚集发光的双端互补核酸适配体探针及黄曲霉毒素B1均相免标记检测方法，CN109490264A
会议报告：
第二届中国（南昌）食品安全快速检测高峰论坛，中国，成都，2023，青年论坛报告
